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![]() | Medion Diagnostics AG CH-3186 Düdingen |
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Anti-Human Globulins
They are used in the direct and indirect Coombs tests. Anti-Human Globulins are available as a green or clear solution. Meanwhile the green solution is used most because it allows for a visual control of the reagent being added. Anti-Human Globulin Mono-Type® This polyspecific Coombs reagent is a mixture of rabbit anti-IgG and mouse monoclonal anti-C3b and anti-C3d. The potent anti-IgG part increases the resistance against neutralization of the Coombs reagent due to incomplete removal of human serum. The use of monoclonal anti-C3b and anti-C3d allows for precise titer adjustment of each individual anti-complement and increases the sensitivity especially for the direct Coombs test. The high specificity is achieved through the complete absence of anti-C4 and anti-T. Characteristics
Monospezific Anti-Human Globulins For the evaluation of positive direct antiglobulin tests a range of monospecific anti-human sera are available: Anti-IgG, Anti-IgA, Anti-IgM, Anti-C3, Anti-C3d, and Anti-C4 |